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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82f6bb1c3644f7cf9e39df10416d75a566d622bab1ad687791a3cc9fb4a6661a' 
  AND token = 'MXAlOxNMENd6uD85LoW+W4mvCYMiPeNyQXCwpjGY4cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}